Methacholine Challenge Test Safety

This presentation reviews the universal safety precautions that should be followed during a methacholine challenge test, as well as reviewing COVID-19 specific safety recommendations

Nebulizer Characterization

Technical Bulletin, nebulizer characterization for the methacholine challenge test

Methapharm Respiratory Blog

Asthma is (not) just asthma

Asthma is (not) just asthma

Asthma is (not) just asthma Isn’t it just asthma? Actually, no. Over the years, the definition of asthma has changed. Rather than a catch-all diagnosis for bronchoconstriction, airway inflammation, wheezing, cough and mucus production, asthma is recognized as an...

Welcome to Our Blog

Welcome to Our Blog

Methapharm Respiratory is proud to work with healthcare practitioners to support the right diagnosis for patients exhibiting common respiratory symptoms such as cough, wheeze, and shortness of breath. We are a trusted partner for bronchoprovocation testing, supplying...

About Provocholine


What is Provocholine?

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What is Provocholine?

Provocholine is the only FDA approved methacholine chloride for the diagnosis of bronchial hyperresponsiveness. A negative methacholine challenge test can essentially rule out asthma.


Frequently Asked Questions

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Here are the answers to the common questions about Provocholine and the methacholine challenge test.

Educational Resources

Online Courses

Free online training courses that can earn you up to three CRCE credits.

Mixing Visuals

Training videos and dilution aids created to assist with the preparation of the three most common dosing protocols.


Links to both international and country specific guidelines that include bronchial challenge testing.


Searchable list with links to the most relevant and recent publications on methacholine challenge testing.