human lung
IS IT ASTHMA?
Clinical studies have suggested that about 30% of patients did not have asthma when objectively assessed.1

Bronchoprovocation testing with methacholine can help to rule out a diagnosis of current asthma.

Methapharm is offering Three Self-Study Training Modules

AARC Members may earn a total of 4.0 hours of CRCE credits

These courses were designed to assist with the implementation of the methacholine challenge test. They also provide a “ready to use” QA program for those currently providing the services.

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Testing Locator
Methapharm has created an online map tool that will allow you to find the locations closest to you offering the methacholine challenge test using Provocholine.
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About Provocholine

What is Provocholine?

Provocholine is the only FDA approved methacholine chloride for the diagnosis of bronchial hyperresponsiveness. A negative methacholine challenge test can essentially rule out asthma.

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FAQ's

Here are the answers to the common questions about Provocholine and the methacholine challenge test.

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Educational Resources

Mixing Visuals

Training videos and dilution aids created to assist with the preparation of the three most common dosing protocols.
Check out the Materials

Guidelines

Links to both international and country specific guidelines that include bronchial challenge testing.
View the Guidelines

Publications

Searchable list with links to the most relevant and recent publications on methacholine challenge testing.
Search Publications

Online Training Courses

Taking the Provocholine Challenge

An in-depth slideshow that will help you to better understand the test. Covering the purpose, equipment, preparation, administration & interpretation.

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Reconstituting Provocholine for Methacholine Challenge Testing

These training videos will take you step by step, through the process of reconstituting Provocholine.

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Ordering Information

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Ordering Information

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Reference: 1) Aaron, S.D., Vandemheen, K.L., FitzGerald, J.M., Ainsle, M, Gupta, S, Lemiere, C,…Boulet, L. (2017). Reevaluation of Diagnosis in Adults with Physician-Diagnosed Asthma. Jama, 317(3):269-279. doi 10.1001/jama.2016.19627